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96
ATCC microorganisms 2026
Microorganisms 2026, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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95
DSMZ klebsiella pneumoniae
The agar well diffusion assay showed the effect of lonafarnib and tipifarnib on the formation of inhibition zones in cultures of different bacterial strains. Control (DMSO), lonafarnib, and tipifarnib (500 μM) were applied to agar plates inoculated with different bacterial strains [ (A) S. aureus , (B) MRSA, (C) S. epidermidis , (D) E. faecium , (E) E. coli , (F) K. <t>pneumoniae</t> , and (G) P. aeruginosa ]. Statistical significance was indicated as follows: ** p < 0.01 and *** p < 0.001. Significant differences between lonafarnib- and tipifarnib-treated S. aureus , MRSA, and S. epidermidis is indicated as follows: ***. n.s. = not significant.
Klebsiella Pneumoniae, supplied by DSMZ, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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The agar well diffusion assay showed the effect of lonafarnib and tipifarnib on the formation of inhibition zones in cultures of different bacterial strains. Control (DMSO), lonafarnib, and tipifarnib (500 μM) were applied to agar plates inoculated with different bacterial strains [ (A) S. aureus , (B) MRSA, (C) S. epidermidis , (D) E. faecium , (E) E. coli , (F) K. pneumoniae , and (G) P. aeruginosa ]. Statistical significance was indicated as follows: ** p < 0.01 and *** p < 0.001. Significant differences between lonafarnib- and tipifarnib-treated S. aureus , MRSA, and S. epidermidis is indicated as follows: ***. n.s. = not significant.

Journal: Frontiers in Microbiology

Article Title: Bacteria Are New Targets for Inhibitors of Human Farnesyltransferase

doi: 10.3389/fmicb.2021.628283

Figure Lengend Snippet: The agar well diffusion assay showed the effect of lonafarnib and tipifarnib on the formation of inhibition zones in cultures of different bacterial strains. Control (DMSO), lonafarnib, and tipifarnib (500 μM) were applied to agar plates inoculated with different bacterial strains [ (A) S. aureus , (B) MRSA, (C) S. epidermidis , (D) E. faecium , (E) E. coli , (F) K. pneumoniae , and (G) P. aeruginosa ]. Statistical significance was indicated as follows: ** p < 0.01 and *** p < 0.001. Significant differences between lonafarnib- and tipifarnib-treated S. aureus , MRSA, and S. epidermidis is indicated as follows: ***. n.s. = not significant.

Article Snippet: The following bacterial strains were used: S. aureus (DSM-799, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), methicillin-resistant Staphylococcus aureus (MRSA) (clinical isolate, kindly provided by B. Ghebremedhin, Helios University Medical Centre, Wuppertal, Germany), Streptococcus pneumoniae ( S. pneumoniae ) (kindly provided by A. Ehrhardt, Witten/Herdecke University, Witten, Germany), E. coli (DSM-11250, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Pseudomonas aeruginosa ( P. aeruginosa ) (DSM-939, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Staphylococcus epidermidis ( S. epidermidis ) (DSM-20044, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Klebsiella pneumoniae ( K. pneumoniae ) (DSM-30104, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), and Enterococcus faecium ( E. faecium ) (DSM-2146, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures).

Techniques: Diffusion-based Assay, Inhibition, Control

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of lonafarnib and tipifarnib on S. aureus , S. epidermidis , S.  pneumoniae  , and E. coli .

Journal: Frontiers in Microbiology

Article Title: Bacteria Are New Targets for Inhibitors of Human Farnesyltransferase

doi: 10.3389/fmicb.2021.628283

Figure Lengend Snippet: Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of lonafarnib and tipifarnib on S. aureus , S. epidermidis , S. pneumoniae , and E. coli .

Article Snippet: The following bacterial strains were used: S. aureus (DSM-799, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), methicillin-resistant Staphylococcus aureus (MRSA) (clinical isolate, kindly provided by B. Ghebremedhin, Helios University Medical Centre, Wuppertal, Germany), Streptococcus pneumoniae ( S. pneumoniae ) (kindly provided by A. Ehrhardt, Witten/Herdecke University, Witten, Germany), E. coli (DSM-11250, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Pseudomonas aeruginosa ( P. aeruginosa ) (DSM-939, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Staphylococcus epidermidis ( S. epidermidis ) (DSM-20044, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Klebsiella pneumoniae ( K. pneumoniae ) (DSM-30104, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), and Enterococcus faecium ( E. faecium ) (DSM-2146, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures).

Techniques: Concentration Assay, Inhibition

The time kill assay revealed the reduction rate of different bacterial strains after treatment with lonafarnib (500 μM) and tipifarnib (500 μM). The effect on (A) S. aureus , (B) MRSA , (C) S. epidermidis , (D) E. faecium , (E) S. pneumoniae , (F) E. coli , (G) P. aeruginosa , and (H) K. pneumoniae was evaluated. Statistical significance was indicated as follows: * p < 0.05; ** p < 0.01; and *** p < 0.001.

Journal: Frontiers in Microbiology

Article Title: Bacteria Are New Targets for Inhibitors of Human Farnesyltransferase

doi: 10.3389/fmicb.2021.628283

Figure Lengend Snippet: The time kill assay revealed the reduction rate of different bacterial strains after treatment with lonafarnib (500 μM) and tipifarnib (500 μM). The effect on (A) S. aureus , (B) MRSA , (C) S. epidermidis , (D) E. faecium , (E) S. pneumoniae , (F) E. coli , (G) P. aeruginosa , and (H) K. pneumoniae was evaluated. Statistical significance was indicated as follows: * p < 0.05; ** p < 0.01; and *** p < 0.001.

Article Snippet: The following bacterial strains were used: S. aureus (DSM-799, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), methicillin-resistant Staphylococcus aureus (MRSA) (clinical isolate, kindly provided by B. Ghebremedhin, Helios University Medical Centre, Wuppertal, Germany), Streptococcus pneumoniae ( S. pneumoniae ) (kindly provided by A. Ehrhardt, Witten/Herdecke University, Witten, Germany), E. coli (DSM-11250, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Pseudomonas aeruginosa ( P. aeruginosa ) (DSM-939, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Staphylococcus epidermidis ( S. epidermidis ) (DSM-20044, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), Klebsiella pneumoniae ( K. pneumoniae ) (DSM-30104, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures), and Enterococcus faecium ( E. faecium ) (DSM-2146, Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures).

Techniques: Time-Kill Assay